Circe
From superman.nu: Supermanica
Circe
An ancient Greek sorceress. In one account, she was originally from another planet and gave Superman an evolution serum, transforming him partially into a lion (Act No. 243, Aug. 1958: "The Lady and the Lion")
In November 1963, with the aid of Proty II, Saturn Woman poses as the enchantress Circe as part of Superman’s plan to defeat the Superman Revenge Squad (S No. 165/1: pts. I-II—â€Beauty and the Super-Beast!â€; “Circe’s Super-Slaveâ€).
She was responsible also for changing Biron the centaur into a horse and later gave him super-powers as Comet the Super-Horse (S No. 176/1, Apr 1965: "The Revenge of the Super-Pets!").