Krypto Mouse
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Krypto Mouse was Fuzzy, little Tommy Ewell's pet mouse, who grew large as a result of an experiment by Professor Egglehead and gained super powers but kept his mouse personality. Krypto Mouse patrolled Smallville for a time, causing some to confuse him at a distance with Superboy. Eventually, Krypto Mouse's abilities faded away and he returned to normal.
(SB No. 65/3, Jul 1958: "The Amazing Adventures of Krypto-Mouse")