Titano
From superman.nu: Supermanica
Titano. A colossal super-powered ape who inadvertantly proved to be a menace to the citizens of Metropolis in general and Superman in particular. Titano was originally a normal-sized chimpanzee named Toto, and was widely considered to be one of the most intelligent apes on Earth. Toto was befriended by Lois Lane when the ace newspaper reporter aided the chimp after he was accidentally struck by a pie during a slapstick comedy act at a televised charity show. Scientists later launched Toto into space aboard an orbiting satellite for a week, an event that, coincidentally, Lois was covering. While in space, the animal's capsule was bombarded by intense radiation emanating from the collision of two meteorites ... one containing traces of uranium, the other being purely composed of green Kryptonite. Upon the capsule's return to Earth, Toto amazingly grew to a height of more than 40 feet and, recognizing Lois as the cinematic King Kong did Faye Wray, picked her up in his gigantic hand. It was at this point that Lois renamed the ape Titano. Though not malicious by nature, Titano's tremendous size and strength soon began causing a great deal of damage to Metropolis. When Superman attempted to stop the simian's escapade, the Man of Steel was knocked to the ground by Titano's incredible new power: Kryptonite vision. However, Lois then used Titano's tendency to imitate the actions of others to get the beast to wear a pair of giant spectacles that Superman had constructed and treated with a lead coating that blocked Titano's K-vision. The Action Ace then hurled the creature back through time to Earth's Mesozoic Era where he would find contentment among creatures of comparable size (S No. 127/3, Feb. 1959: "Titano the Super-Ape").