Ultra-Humanite
A fiendish "mad scientist" (Act No. 17, Oct 1939), hopelessly paralyzed from the waist down and confined to a wheelchair, whose "great goal" is the "domination of the Earth" (Act No. 14, Jul 1939; and others). Portrayed as nearly bald in two texts (Act No. 13, Jun 1939; Act No. 19, Dec 1939), and as completely bald in two others (Act No. 14, Jul 1939; Act No. 17, Oct 1939), he is a "mental giant" -- the "head of a vast ring of evil enterprises" -- whose fiery eyes burn with terrible hatred and sinister intelligence.
His real name is never stated in the chronicles, but he has been known as the Ultra-Humanite -- Ultra, for short -- ever since "a scientific experiment resulted in [his] possessing the most agile and learned brain on Earth!"
"--Unfortunately for mankind," proclaims the villain in June 1939, "I prefer to use this great intellect for crime. My goal? DOMINATION OF THE WORLD!!" (Act No. 13)
In June 1939 Superman sets out to smash the so-called Cab Protective League, an underworld organization, headed by a racketeer named Reynolds, which is attempting to seize control of the city's lucrative taxi trade by launching a reign of terror against the independent cab companies, murdering their drivers and demolishing their taxicabs in an effort to coerce the independents into joining the League. Finally defeated and apprehended by Superman, Reynolds is convicted of his crimes and sentenced to a term in the Sing Sing penitentiary. However, while en route to the prison by automobile, under police guard, Reynolds asks for, and recieves, permission to smoke a cigarette, and within moments, he has knocked his police escort unconscious by exhaling smoke from a specially prepared cigarette containing "a mysterious gas," hurled from the unconscious policemen from the speeding car, and made good his escape. Superman finally corners Reynolds at his secluded cabin hideout and is about to take him into custody when his attention is called to a second figure in the cabin, a "paralysed cripple" whose "fiery eyes...burn with a terrible hatred and sinister intelligence."